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Collectively, hypercholesterolemia is a causative risk factor for AD, and 27-OHC is likely a potential mechanism for hypercholesterolemia to promote AD pathology

In addition, we may experience vague and unclear symptoms in the early stages, such as general fatigue, muscle aches, waking up tired

Antidepressants with high risk of liver injury, such as iproniazid, phenelzine, imipramine, amitriptyline, duloxetine, bupropion, or agomelatine should be avoided 4,180

The C-2 proton of the thiazolium ring is much more acidic than most =CH groups in other molecules