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van Vliet AR, Verfaillie T, Agostinis P

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For instance, in a rat model of Lipopolysaccharide (LPS)-induced renal dysfunction, EC treatment significantly reduced NF-B p65 phosphorylation at Ser536 and lowered the nuclear-to-cytoplasmic p65 ratio, while preventing IB degradation, indicating its capacity to suppress NF-B activation and mitigate renal inflammation (Prince et al., 2017)

Hasek BE, Stewart LK, Henegan TM, Boudreau A, Lenard NR, Black C, Shin J, Hypens P, Malloy VL, Plaisance EP, Krajcik RA, Orentreich N, Gettys TW: Dietary methionine restriction enhances metabolic flexibility and increases uncoupled respiration in both fed and fasted states