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doi: 10.1016/j.clp.2009.07.011

By increasing reliance on fat as a primary fuel source, L-Carnitine helps preserve muscle glycogen a critical carbohydrate energy reserve during high-intensity training
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Although the mechanism is not known, acetyl CoA from ALCAR metabolism may have been used for synthesis of acetylcholine, which may have contributed to enhanced cholinergic neurotransmission [126]

It is recommended that acetyl l-carnitine is taken first thing in the morning on an empty stomach so that the compound is rapidly digested to help activate the brain from the get-go
