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Statements Author contributions RD and TP conceptualized the review

Acupuncture bidirectionally modulates the release of immune cytokines, forming a complex network with multiple effects on IS

Preclinical studies have indicated the presence of a significant capacity for boosting NAD + levels

Concurrently, the exogenous application of GABA demonstrated a mitigating effect by preserving membrane stability through the reduction of lipid peroxidation product formation (Abd Elbar et al

Out of these, the number of infection-related AE reports for belimumab, rituximab, adalimumab, etanercept, infliximab, golimumab and certolizumab pegol were 1,913 (1.07%), 21,380 (12.00%), 50,345 (28.25%), 54,363 (30.51%), 25,972 (14.57%), 15,721 (8.82%) and 8,521 (4.78%), respectively