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Its the Achilles' heel of so much research

Temozolomide: A review of its discovery, chemical properties, pre-clinical development and clinical trials

Assimakopoulos SF, Maroulis I, Patsoukis N, Vagenas K, Scopa CD, Georgiou CD, Vagianos CE: Effect of antioxidant treatments on the gut-liver axis oxidative status and function in bile duct-ligated rats

doi: 10.3389/fcell.2014.00049 Received 20 June 2014 Accepted 22 August 2014 Published 09 September 2014 Volume 2 - 2014 Edited by Jeff Schwartz, Griffith University, Australia Reviewed by Abhijit Shukla, Harvard Medical School, USA