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It is designed to selectively disrupt the FOXO4-p53 interaction in senescent cells, enabling their targeted clearance while sparing healthy cells in preclinical models
Although its tumoricidal properties hold therapeutic promise, its clinical application in lower gastrointestinal diseases and cancers remains challenging
Diehl JJ, Schmitt LM, Villano M, Crowell CR
The impairment of the balance between GSH and GSSG usually induces loss of ability to control oxidative stress (Couto et al
