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This has driven studies into its effects on muscle strain, tendon integrity, ligament resilience, and joint health

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PLoS ONE 9:e101078

Teng, L

Upon entering systemic circulation and reaching bone tissue, 5-HT attaches to the 5-HTR1B receptor on osteoblasts, which inhibits cAMP response element-binding protein (CREB) activity and cyclin expression, thereby suppressing osteoblast proliferation and differentiation and ultimately hindering bone formation (256)
