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A decrease in cellular GSH content increases oxidative stress [44]
In summary, the molecular mechanisms associated with obesity and IR play a pivotal role in the development of the SLCI in PCOS (140)
From these considerations, it emerges that GSH cannot be considered a mere free radical scavenger but that it has a weighty role in the network governing the choice between survival, necrosis and apoptosis [9,10] as well as in cell signaling [10,11] and metabolism [3,12]
doi:10.1038/ncomms1722
