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doi: 10.1016/J.PNPBP.2020.110145

M1 macrophages are pro-inflammatory, useful in the very early stages of healing for clearing debris but destructive if they persist

In the tumor tissues of liver cancer patients, larger mitochondria were observed, accompanied with raised expression of OPA1 and Mfn1, indicating enhanced mitochondrial fusion in tumor tissues, which promoted metabolism and tumor growth

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Oncoimmunology 8 (9), e1629259