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(2021) 14:dmm045963

The epigenetic effects of amyloid-beta(1-40) on global DNA and neprilysin genes in murine cerebral endothelial cells

and the use of mice that did not exhibit DM

Neither peptide is FDA-approved for human therapeutic use

It should also be noted that a large number of the studies investigating the effects APOE genotype on AD presentation have focused on probable AD patients
