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indicates that the combination of both drugs, administered in low doses for 30 days to middle-aged men with impaired functional and structural characteristics of arterial walls, leads to an increase in the expression of Sirt1 (1.8 times), telomerase activity, the catalytic subunit of AMP 2 protein kinase (PRKAA) (1.5 times), and the KLOTHO gene (1.7 times) after just 30 days of treatment [132]

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Dihexa (PNB-0408) is a synthetic peptide derived from angiotensin IV, developed at Washington State University

Key domains include: Infectious disease models (viral, bacterial, and fungal), including hepatitis, respiratory infections, tuberculosis, and opportunistic infections, where TA1 is used to explore enhanced pathogen clearance and immune resilience
