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Safety, efficacy, and cardiovascular benefits of combination therapy with SGLT-2 inhibitors and GLP-1 receptor agonists in patients with diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials

[DOI] [PMC free article] [PubMed] [Google Scholar] 7.Low Wang CC, Everett BM, Burman KD, Wilson PWF

Updated 1 August 2017

Autophagy The impairment of autophagy and the clearance of accumulated, unwanted proteins play crucial roles in the development of neurodegeneration

Collectively, the available evidence suggests that treatment with SGLT2i could ameliorate clinical outcomes in patients with DM and HFpEF
