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The L-0.9 mg 1-10 hydrogel formulation exhibited a C max of 620 110 ng/mL (observed on day 9), while the L-0.9 mg 2-10 hydrogel formulation exhibited a C max of 930 350 ng/mL (observed on day 20) with relatively steady plasma concentrations throughout the duration of the study (Figure 4D, Table S2)

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