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The clinical trial with ROSE-010 demonstrated its efficacy in acute pain relief for IBS patients and correlation between serum GLP-1 levels and abdominal pain severity further supports the role of GLP-1R agonists in managing visceral pain

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Henceforth, researchers devised numerous strategies for drug development, mainly by evading the enzymatic degradation of bioactive GLP-1 peptide by DPP-4

Understanding how these medications influence appetite, metabolism, and body composition can help individuals make informed decisions about their health

Madamanchi A -Adrenergic receptor signaling in cardiac function and heart failure
