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Vitamins skip the gut entirely, which means your body absorbs almost the full dose

In another 2017 Further, men who were smokers and supplemented with greater than 20 mg of vitamin B6 or 55 mcg of B12 were 2.9 times and 3.7 times more likely to develop lung cancer, respectively

doi: 10.1097/EDE.0000000000000804

This is why ex vivo findings need to be confirmed in human trials which subsequent studies like the 2016 GHK peptide clinical trial and the 2021 copper tripeptide serum trial have done
