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Classical fish contaminants are the heavy metals, with Hg being worthy of mention in this review because it acts as an environmental trigger of autoimmunity (17, 4451), a mechanism that has also been observed for cadmium (Cd) (5155)
(PubMed) Knudsen N, Brix TH
doi: 10.1096/fj.07-099150
Moreover, TMAO can affect T cell transcriptional profiles
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